QTc thresholds are sex-specific.

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Multiple Choice

QTc thresholds are sex-specific.

Explanation:
Sex differences in QTc reflect hormonal effects on ventricular repolarization, so normal QTc ranges are not the same for men and women. In practice, a normal upper limit is about 450 ms for men and about 470 ms for women. When QTc goes beyond these sex-specific cutoffs, it’s considered prolonged and raises the risk of torsades de pointes, especially with QT-prolonging factors. That explains why the correct choice states men should be below 450 ms and women below 470 ms. The idea of the same threshold for both sexes is inaccurate, and the alternative numbers aren’t the standard cutoffs used. QTc is indeed used in assessment.

Sex differences in QTc reflect hormonal effects on ventricular repolarization, so normal QTc ranges are not the same for men and women. In practice, a normal upper limit is about 450 ms for men and about 470 ms for women. When QTc goes beyond these sex-specific cutoffs, it’s considered prolonged and raises the risk of torsades de pointes, especially with QT-prolonging factors.

That explains why the correct choice states men should be below 450 ms and women below 470 ms. The idea of the same threshold for both sexes is inaccurate, and the alternative numbers aren’t the standard cutoffs used. QTc is indeed used in assessment.

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